Effect of ivermectin on two filaria-vector pairsBrugia malayi-Aedes aegypti ; Litomosoides sigmodontis-Bdellonyssus bacoti1

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Ivermectin and moxidectin in two filarial systems: resistance of Monanema martini; inhibition of Litomosoides sigmodontis insemination.

Effects of ivermectin and moxidectin were compared on two filarial species: Monanema martini which presents dermal microfilariae and induces Onchocerca-like lesions in its natural murid host Lemniscomys striatus, and Litomosoides sigmodontis (= L. carinii). M. martini microfilariae showed an unusual resistance to ivermectin, in vitro and in vivo; moxidectin was no more efficient. However, the t...

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The Chemokine CXCL12 Is Essential for the Clearance of the Filaria Litomosoides sigmodontis in Resistant Mice

Litomosoides sigmodontis is a cause of filarial infection in rodents. Once infective larvae overcome the skin barrier, they enter the lymphatic system and then settle in the pleural cavity, causing soft tissue infection. The outcome of infection depends on the parasite's modulatory ability and also on the immune response of the infected host, which is influenced by its genetic background. The g...

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Aedes aegypti as a Vector of Flavivirus

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ژورنال

عنوان ژورنال: Annales de Parasitologie Humaine et Comparée

سال: 1993

ISSN: 0003-4150

DOI: 10.1051/parasite/1993683144